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The animal stands still for a long time, indifferent to the environment.
There are signs of damage to the nervous system. When moving forward, the animal makes jerky movements, falls, rises and falls again, rows its limbs or lies in a coma. Convulsive muscle contractions are observed, the head is thrown back. Death occurs in 2-3 days, sometimes in 5-7 days. The subacute course of the disease occurs in adult sheep and lambs, sometimes it is a continuation of a hyperacute or acute course. In animals, digestion is disturbed, there is no appetite, thirst, diarrhea appear, fatness is quickly lost.
- The gait is shaky, paresis of the limbs develops.
- In the acute course of the disease, body temperature rises to 41 ° C, depression, loss and perversion of doxycycline, diarrhea with streaks of blood and mucus are noted.
Stools thin, offensive, with mucus and blood. The illness lasts 10-12 days. Pregnant sheep are often aborted. Body temperature within 40 °C. Reflexes are weakened. When the animal recovers, the appetite improves, the functions of the gastrointestinal tract are restored.
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A chronic course is observed in sheep of poor fatness. Sick animals are weak, depressed, drowsy, anemic, refuse to feed, they have pronounced nervous phenomena. Sheep grow thin to the point of complete exhaustion. In lambs with a chronic course, there is no appetite, lethargy, trembling, colic, diarrhea, and nervous phenomena are observed. In some cases, some animals recover.
doxycycline is made on the basis of epidemiological data, clinical signs, pathological changes and laboratory results. At the same time, it is necessary to examine the contents of the small intestine for the presence of a toxin produced by pathogens in a neutralization reaction.
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In the laboratory, microscopy of smears prepared from cultures and pathological material is carried out isolate a pure culture of the microbe and determine its virulence in laboratory animals.
Fresh pieces of parenchymal organs, tubular bone, affected areas of the abomasum and duodenum, contents of the small intestine, lymph nodes, blood from the heart are sent to the laboratory.
Infectious anaerobic enterotoxemia of sheep.
In all cases, against these infections in sheep, intense and long-term immunity is created.
Dead animals are burned along with the skin. Do not milk or use the milk of sick sheep. The movement of animals, the slaughter and use of the meat of sick sheep, shearing, and castration are prohibited.
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Immunity is type-specific and develops primarily against major toxins.
Prevention and control measures. They create conditions for the normal development of animals, organize full-fledged feeding, prevent and eliminate factors that cause indigestion in sheep. Enterotoxemia in vivo causes immunity lasting up to a year.
In stationary disadvantaged for clostridium farms with therapeutic and preventive purposes, feed antibiotics were tested at the rate of 0.25-1 kg of kormogrizin, 0.5-1 kg of biovit, 1-1.5 kg of batsichilin per 1 quintal of concentrated feed. As a result, the loss of lambs in flocks decreased by 4.2 times.
It is recommended to use drugs of the tetracycline group intramuscularly for 4-5 days at a dose of 2.5-5 mg per 1 kg of animal weight. Synthomycin is given orally at a dose of 0.5-1 mg for doxycycline pills sheep and 0.2 g for lambs. In disadvantaged flocks, a suspension of long-acting antibiotics is used for lambs for therapeutic and prophylactic purposes.
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